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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R12B
All Species:
22.42
Human Site:
Y619
Identified Species:
70.48
UniProt:
O60237
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60237
NP_002472.1
982
110404
Y619
A
R
E
K
R
R
S
Y
L
T
P
V
R
D
E
Chimpanzee
Pan troglodytes
XP_514103
998
112324
Y619
A
R
E
K
R
R
S
Y
L
T
P
V
R
D
E
Rhesus Macaque
Macaca mulatta
XP_001106168
998
112396
Y619
A
R
E
K
R
R
S
Y
L
T
P
V
R
D
E
Dog
Lupus familis
XP_547351
983
110257
Y620
A
R
D
R
R
R
S
Y
L
T
P
V
R
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG95
976
109031
Y618
A
R
E
K
R
R
S
Y
L
T
P
V
R
D
E
Rat
Rattus norvegicus
Q10728
1032
115264
Y670
V
R
E
R
R
R
S
Y
L
T
P
V
R
D
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90623
1004
111588
A641
A
P
S
V
V
N
A
A
A
T
T
T
A
M
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DRG7
1049
117303
E651
L
L
S
R
Y
W
A
E
E
S
A
E
K
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
95
92.3
N.A.
89.8
49.4
N.A.
N.A.
48.5
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.6
96.8
95.4
N.A.
93.4
65.8
N.A.
N.A.
65.4
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
100
86.6
N.A.
N.A.
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
20
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
75
0
0
0
0
0
25
13
13
0
13
0
13
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
13
0
0
0
0
0
0
0
0
0
0
75
0
% D
% Glu:
0
0
63
0
0
0
0
13
13
0
0
13
0
13
75
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
50
0
0
0
0
0
0
0
0
13
0
13
% K
% Leu:
13
13
0
0
0
0
0
0
75
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
13
0
0
0
0
0
0
0
0
75
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
75
0
38
75
75
0
0
0
0
0
0
75
0
0
% R
% Ser:
0
0
25
0
0
0
75
0
0
13
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
88
13
13
0
0
13
% T
% Val:
13
0
0
13
13
0
0
0
0
0
0
75
0
0
0
% V
% Trp:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _